DPCstruct | MC22398

Metacluster Properties and Pfam Annotations

Number of structural domains1150
Mean domain length (aa)126 ± 25 aa
Standard deviation of domain lengths24.69
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score83.62
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)16.11
Pfam Score92.77
Assigned Pfam label(s) CL0084- PF07335- CL0029- CL0229- CL0209

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U0VGW9 176-309 None
A0A538QE54 1-131 None
A0A538Q4G2 26-131 None
A0A444XRJ7 34-134 None
A0A1F2VSF5 235-340 None
A0A6A6L9H4 146-273 None
A0A7K2YAA5 74-175 None
A0A146H7U7 520-621 None
A0A838RK17 19-130 None
D9TP07 141-251 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.