DPCstruct | MC22054

Metacluster Properties and Pfam Annotations

Number of structural domains1545
Mean domain length (aa)225 ± 53 aa
Standard deviation of domain lengths53.11
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score74.81
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)18.19
Pfam Score83.21
Assigned Pfam label(s) PF03105- PF05216- PF04987- PF17830- PF04770

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2K3PDQ8 62-307 None
A0A2K3PDJ7 199-442 None
A0A5A7QEZ1 91-347 None
A0A388MDY7 187-398 None
A0A7J0DQW7 333-545 None
A0A0Q3PQE6 66-299 None
A0A2K2CJK6 49-267 None
A0A453GGX6 2-183 None
A0A7J0HCS5 767-1024 None
A0A7J0HA85 16-184 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.