DPCstruct | MC22054

Metacluster Properties and Pfam Annotations

Number of structural domains1545
Mean domain length (aa)225 ± 53 aa
Standard deviation of domain lengths53.11
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score74.81
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)18.19
Pfam Score83.21
Assigned Pfam label(s) PF03105- PF05216- PF04987- PF17830- PF04770

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A699JSK0 449-671 None
A0A699JL52 73-282 None
A0A7J0DPN4 86-394 None
A0A6I9SWE2 411-655 None
A0A388M6D8 72-311 None
A0A388LP08 360-624 None
M5WUT1 16-186 None
M5WUN4 1-154 None
A0A2K3PRY3 177-458 None
A0A2K3PE67 31-272 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.