DPCstruct | MC22031

Metacluster Properties and Pfam Annotations

Number of structural domains552
Mean domain length (aa)114 ± 17 aa
Standard deviation of domain lengths16.82
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score83.29
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)15.11
Pfam Score94.03
Assigned Pfam label(s) CL0257- CL0123- CL0020- CL0310- CL0311

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A524MEK5 31-155 None
A0A3A3Z3C5 159-298 None
A0A2D8RCN6 450-573 None
A0A1H1IA21 254-366 None
A0A2D5I081 8-144 None
A0A841RDQ2 10-114 None
A0A7K0VHN7 5-94 None
A0A1H5X3Y9 4-84 None
A0A2P8Z699 389-505 None
A0A654H7I8 580-694 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.