DPCstruct | MC22031

Metacluster Properties and Pfam Annotations

Number of structural domains552
Mean domain length (aa)114 ± 17 aa
Standard deviation of domain lengths16.82
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score83.29
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)15.11
Pfam Score94.03
Assigned Pfam label(s) CL0257- CL0123- CL0020- CL0310- CL0311

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6L8HW75 203-303 None
A0A178M8X5 254-358 None
A0A2G6E5H9 86-196 None
A0A1Q9RTH8 177-283 None
A0A817U118 720-841 None
A0A4Z0KZ53 536-653 None
A0A1F9MDR0 17-137 None
A0A0G2YEZ7 100-196 None
A0A2A5CSL5 3-92 None
A0A4P5R9L1 82-190 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.