DPCstruct | MC21954

Metacluster Properties and Pfam Annotations

Number of structural domains420
Mean domain length (aa)214 ± 46 aa
Standard deviation of domain lengths45.76
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score85.62
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)20.18
Pfam Score99.13
Assigned Pfam label(s) CL0125- PF20108- CL0716- CL0366- PF05634

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6D0EPG3 1-139 FNPAVTLGLWAGGRFPAKDIIGYVVAQVVGGIIAAAILYVIASGKAGFDATASGFASNGFGEHSPGGFSMLSAIVIEIVLTAGFLLV…
J3FRV8 12-228 LGTFWLVLGGCGSAVIAASSPLGIGVLGVALAFGLTVLTMAFAIGHISGCHLNPAVSVGLFVGGRFPAKELPAYIIAQVLGAILAAA…
A0A843X586 98-271 None
A0A7J6PYS9 6-151 None
A0A446PIY5 24-152 None
A0A5P1F9G6 5-181 None
A0A4S4DAX3 241-458 None
A0A2C9JL65 2-116 None
A0A813BUL8 25-242 None
A0A150NT78 8-281 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.