DPCstruct | MC21954

Metacluster Properties and Pfam Annotations

Number of structural domains420
Mean domain length (aa)214 ± 46 aa
Standard deviation of domain lengths45.76
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score85.62
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)20.18
Pfam Score99.13
Assigned Pfam label(s) CL0125- PF20108- CL0716- CL0366- PF05634

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U0VTU3 204-456 None
A0A5N5HIG1 156-376 None
A0A5R8NSP4 1-169 None
A0A177VFK6 3-177 None
A0A654H7P0 90-382 None
R7QKP1 962-1227 None
A0A6V8HF56 42-322 None
A0A183TKH2 10-181 None
A0A6A2XB94 185-417 None
A0A6U3RV48 2-278 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.