DPCstruct | MC19890

Metacluster Properties and Pfam Annotations

Number of structural domains189
Mean domain length (aa)125 ± 20 aa
Standard deviation of domain lengths20.14
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score82.73
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)18.29
Pfam Score93.37
Assigned Pfam label(s) PF02470- PF02405- PF11887

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A377QFI5 158-295 None
A0A1R1LYR3 266-380 None
A0A840VAQ9 150-282 None
A0A2X1KQF9 201-323 None
A0A2X1NGF1 44-166 None
E8R5N3 377-470 None
A0A7W0AJR4 34-152 None
A0A2N7QMY7 34-152 None
A0A4P9VST1 134-260 None
A0A140GUK6 25-155 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.