DPCstruct | MC19890

Metacluster Properties and Pfam Annotations

Number of structural domains189
Mean domain length (aa)125 ± 20 aa
Standard deviation of domain lengths20.14
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score82.73
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)18.29
Pfam Score93.37
Assigned Pfam label(s) PF02470- PF02405- PF11887

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2W1MWE1 4-132 None
A0A2U8E236 2-85 None
A0A1B2LWA9 1-203 None
A0A538KA32 27-176 None
A0A538KDW9 107-235 None
I1LWB0 117-248 None
A0A3M1FXB0 27-161 None
A0A521VXQ5 27-145 None
A0A7J7AVF6 245-415 None
K2EH04 1-101 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.