DPCstruct | MC19890

Metacluster Properties and Pfam Annotations

Number of structural domains189
Mean domain length (aa)125 ± 20 aa
Standard deviation of domain lengths20.14
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score82.73
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)18.29
Pfam Score93.37
Assigned Pfam label(s) PF02470- PF02405- PF11887

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1F6TNF2 3-109 NGYKIKARFDNIGGLKVKAAVTMAGVRIGRVSDITFDTGKYQAVVTMDVDGRYKTLPTDTSATILTAGLLGEQYVGLEPGAEEEYLK…
D0X0W9 9-130 VKSIHDAGQRVQIYFSDAAGLVAGRTTIRYQGLEVGMVRDINLTEDLGSIYVDADIYPEAAKLLNDKTRFWLVKPTASLTGVSGLDA…
A0A0S6W578 28-142 None
M1PHR4 154-273 None
A0A7D5MYA9 13-191 None
A0A3E1E8G9 17-159 None
A0A2N9YA63 58-163 None
A0A1A9VJV1 128-239 None
A0A4R1IFA7 54-157 None
A0A4U9HCJ7 22-151 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.