DPCstruct | MC19890

Metacluster Properties and Pfam Annotations

Number of structural domains189
Mean domain length (aa)125 ± 20 aa
Standard deviation of domain lengths20.14
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score82.73
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)18.29
Pfam Score93.37
Assigned Pfam label(s) PF02470- PF02405- PF11887

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A378NAM5 43-164 None
A0A6I7W4I7 99-204 None
A0A142WPX8 255-367 None
X8A3R3 1-95 None
A0A519N9R6 296-420 None
A0A429Z2D7 13-154 None
A0A7V0IAM1 22-141 None
A0A7N2KZB6 107-247 None
A0A537IGW8 269-376 None
A0A287QC45 211-342 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.