DPCstruct | MC18893

Metacluster Properties and Pfam Annotations

Number of structural domains1842
Mean domain length (aa)152 ± 26 aa
Standard deviation of domain lengths25.61
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score85.63
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)16.29
Pfam Score97.65
Assigned Pfam label(s) CL0125- CL0244- CL0043- CL0037- PF10844

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Z0YJP1 173-344 None
A0A1Q8LM32 4-131 None
A0A4R7ABQ2 50-168 None
C9RD66 5-165 None
A0A4R5AIS5 499-670 None
A0A2S8A7Z3 2-163 None
A0A150WE49 12-161 None
A0A0A8K0P6 39-145 None
A0A5C5TEJ7 26-188 None
A0A5C5SIE3 112-313 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.