DPCstruct | MC18893

Metacluster Properties and Pfam Annotations

Number of structural domains1842
Mean domain length (aa)152 ± 26 aa
Standard deviation of domain lengths25.61
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score85.63
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)16.29
Pfam Score97.65
Assigned Pfam label(s) CL0125- CL0244- CL0043- CL0037- PF10844

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1H1FEV7 5-151 IEKFIKLLESELGYKEKGNGYTKFGKWYNSVDSKYDYSKLPWCDMFISWAAKKLGYEEWIGQFAWTPSHARWFEKQDAFGKKPEVGA…
D1AQ23 15-170 FGFSKKTYDETKFRQELIDWASSKVGAAYSMENRWGENTYDCSSFISRGLRETGMISVSGKKSDYGTTARGLYNNSGQKIEKDDYGL…
A0A356U9Z0 151-329 None
A0A486XG52 22-157 None
A0A1Y4TRB5 265-445 None
A0A2N3I0H2 102-311 None
A0A4R2JQG8 239-407 None
A0A3E2YGG4 4-120 None
A0A2N2C4L7 4-184 None
A0A537IE92 49-247 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.