DPCstruct | MC18893

Metacluster Properties and Pfam Annotations

Number of structural domains1842
Mean domain length (aa)152 ± 26 aa
Standard deviation of domain lengths25.61
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score85.63
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)16.29
Pfam Score97.65
Assigned Pfam label(s) CL0125- CL0244- CL0043- CL0037- PF10844

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A375HV42 5-187 None
A0A7W1F7B0 1-143 None
A0A552UXH9 810-976 None
A0A2V4NEM3 17-186 None
A0A1F6WQN1 1-129 None
A0A1U7NHL1 4-177 None
A0A6I5X2A0 116-231 None
A0A1S1X2V1 471-715 None
A0A1H6KCE5 57-202 None
A0A850CUP4 117-233 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.