DPCstruct | MC18893

Metacluster Properties and Pfam Annotations

Number of structural domains1842
Mean domain length (aa)152 ± 26 aa
Standard deviation of domain lengths25.61
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score85.63
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)16.29
Pfam Score97.65
Assigned Pfam label(s) CL0125- CL0244- CL0043- CL0037- PF10844

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4P0Z954 25-168 None
A0A2M7BBD7 659-820 None
A0A4Q1TAX8 155-316 None
A0A2W4HRU1 44-205 None
A0A3B8JC14 124-244 None
E4T6J4 40-180 None
A0A365HEU4 1-167 None
A0A365H692 217-346 None
A0A1Z4SXV4 34-205 None
A0A2E6S8I2 312-454 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.