DPCstruct | MC18812

Metacluster Properties and Pfam Annotations

Number of structural domains355
Mean domain length (aa)170 ± 31 aa
Standard deviation of domain lengths30.84
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score88.43
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)14.63
Pfam Score82.25
Assigned Pfam label(s) PF00557- CL0356- CL0732

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A445J9C3 24-269 None
A0A534ZRY1 2-167 None
A0A0K2RGF2 25-163 None
A0A7H4MB22 1-142 None
A0A662Y2N1 9-179 None
A0A6T8N3D5 1-202 None
A0A3Q0E3C8 41-201 None
A0A2G6C5Y7 512-690 None
A0A168IHW6 105-283 None
A0A4R0R4L7 6-188 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.