DPCstruct | MC18812

Metacluster Properties and Pfam Annotations

Number of structural domains355
Mean domain length (aa)170 ± 31 aa
Standard deviation of domain lengths30.84
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score88.43
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)14.63
Pfam Score82.25
Assigned Pfam label(s) PF00557- CL0356- CL0732

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Y0RQX3 62-237 MPTEAVGQSSESKRKEIAQLVTKAGADSAVITALDSICWLLNVRGLDVSRLPVLLSHAILHADSSVEYFLDPARLPAEFAAHVGTGV…
A0A1D6KDB6 22-189 GITNEEYISRRKKLLEVLPEKSLAIIASADQQMMTDVVPYPFRQNGDYLYITGCTQPGGVAVLSEETGFCMFMPDTNKEDLVWQGET…
A0A1F8P9Q6 29-233 None
A0A379AHS1 24-222 None
R9P3J3 522-682 None
C3ZF22 567-786 None
C3ZF57 98-255 None
A0A1V8S8S6 16-185 None
A0A534W7R4 7-183 None
A0A7M3RN36 7-217 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.