DPCstruct | MC18456

Metacluster Properties and Pfam Annotations

Number of structural domains48
Mean domain length (aa)322 ± 55 aa
Standard deviation of domain lengths54.87
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score74.22
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)38.33
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A446TM56 6-258 None
A0A1Z5K6I5 538-851 None
A0A1D6JMD4 254-529 None
A0A453QXY6 283-608 None
A0A7J9ASX6 149-399 None
A0A7R9VCT1 213-602 None
A0A287JMJ2 11-244 None
A0A2G2ZVZ7 480-748 None
A0A1D6H5P0 160-567 None
A0A453K1H1 1-264 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.