DPCstruct | MC18456

Metacluster Properties and Pfam Annotations

Number of structural domains48
Mean domain length (aa)322 ± 55 aa
Standard deviation of domain lengths54.87
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score74.22
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)38.33
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
M5BIB0 245-596 EKRTALQLLVSFNRIWVVHISLFWYYAAYNSPVIYRRAGSRDATAAMKWSASALGGAVSAAIMIAATLAEFTFIPTTWNNTSHLTRR…
A0A287L7E4 2-299 LIVSWSSSGSLSGIADATVFRSVLSVFITAALLNFIKVTLDILLTFQAWGSMEWTQILRYLLKFFVAIAWIIILPVTYSSSIKSPSG…
A0A2P2MBJ8 472-850 None
A0A453Q8I0 118-527 None
A0A453Q8N9 33-355 None
A0A453Q8Q3 362-770 None
A0A7C9EUH7 139-411 None
A0A287RHA0 309-618 None
A0A287PW09 198-619 None
A0A446PQL0 13-297 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.