DPCstruct | MC18168

Metacluster Properties and Pfam Annotations

Number of structural domains489
Mean domain length (aa)125 ± 19 aa
Standard deviation of domain lengths18.56
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score85.02
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)31.62
Pfam Score99.28
Assigned Pfam label(s) PF01412- CL0154- CL0110- CL0080- CL0192

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y1WL66 543-673 None
A0A812NIT7 3-116 None
A0A0A8L5C7 12-147 None
A0A1W0A1Y8 985-1099 None
D3B9L6 5-135 None
D3B391 5-137 None
A0A7J8LJ89 243-329 None
B2G410 136-260 None
A0A1X7TXQ5 744-866 None
A0A1X7TTF8 172-300 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.