DPCstruct | MC18168

Metacluster Properties and Pfam Annotations

Number of structural domains489
Mean domain length (aa)125 ± 19 aa
Standard deviation of domain lengths18.56
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score85.02
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)31.62
Pfam Score99.28
Assigned Pfam label(s) PF01412- CL0154- CL0110- CL0080- CL0192

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J6PFG0 276-426 None
A0A7J6PDQ1 504-641 None
A0A7J6PCC4 400-529 None
A0A4V4M5S9 414-541 None
A0A654GNS6 633-755 None
T5A6E0 8-146 None
A0A5E4QEH4 8-133 None
S4R5R7 1-99 None
A0A7S1ZAN5 16-143 None
A0A6S9GUJ2 92-245 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.