DPCstruct | MC17772

Metacluster Properties and Pfam Annotations

Number of structural domains152
Mean domain length (aa)146 ± 23 aa
Standard deviation of domain lengths22.83
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score86.23
Mean fraction of residues predicted as intrinsically disordered0.42
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)18.85
Pfam Score98.65
Assigned Pfam label(s) PF14449- CL0695

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K4IER9 29-160 RGTKFKPEVVYSFIHASIGRIKNGNVTGVHFYNPERVWIIKILKTNETNKTFLADFEFYDIDNKKWIHKKTPSSFFPADWNIATLLM…
A0A2V3W6W4 35-175 EINEVTAITDLEHTEYFRNLALEHILEGEINKKGAAVGFHYDRLPTKKGEVIEGTETKPNELGVYEAEVVVNHVEKTSNGGKSTFFP…
A0A8B2DGZ1 5-123 None
A0A0Q5GLU2 78-247 None
J8HPU4 2-102 None
A0A7H1N2B1 5-157 None
A0A1V5R3R0 809-934 None
A0A850KCU3 17-149 None
A0A2S0UEB1 615-762 None
W7DCI7 62-202 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.