DPCstruct | MC17772

Metacluster Properties and Pfam Annotations

Number of structural domains152
Mean domain length (aa)146 ± 23 aa
Standard deviation of domain lengths22.83
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score86.23
Mean fraction of residues predicted as intrinsically disordered0.42
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)18.85
Pfam Score98.65
Assigned Pfam label(s) PF14449- CL0695

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
U2Q9S5 77-245 None
C2WXI3 140-292 None
A0A2E7K7A5 2-124 None
A0A1M7RS73 740-877 None
A0A329EMP1 44-221 None
A0A2D0A689 80-213 None
A0A8A8BWY7 58-198 None
A0A0W7YIG9 3-159 None
A0A1X7PAG1 705-851 None
D0LPG8 442-641 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.