DPCstruct | MC14446

Metacluster Properties and Pfam Annotations

Number of structural domains824
Mean domain length (aa)146 ± 33 aa
Standard deviation of domain lengths32.70
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score76.72
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)26.06
Pfam Score99.45
Assigned Pfam label(s) CL0277- CL0108- CL0123- PF09316- CL0073

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4V4H2U3 32-156 None
A0A7E4UPM8 1-142 None
A0A4Q4WCY1 52-199 None
D3BSH9 250-391 None
A0A1J4KYA3 43-211 None
A0A1J4KYU8 137-283 None
G4Z5M4 230-450 None
A0A438K8K6 208-312 None
A0A420HRX5 67-201 None
A0A6L2MRB8 108-203 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.