DPCstruct | MC14446

Metacluster Properties and Pfam Annotations

Number of structural domains824
Mean domain length (aa)146 ± 33 aa
Standard deviation of domain lengths32.70
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score76.72
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)26.06
Pfam Score99.45
Assigned Pfam label(s) CL0277- CL0108- CL0123- PF09316- CL0073

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
J9ILM8 431-580 None
J9IXE8 230-378 None
A0A7S4IXM9 329-499 None
A0A369SIG4 313-459 None
A0A0L7LT06 279-413 None
A0A6L2KFQ0 446-524 None
A0A1X7R735 250-361 None
Q24HY5 120-233 None
A0A444D830 5-135 None
A0A2T7IHP5 313-441 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.