DPCstruct | MC13540

Metacluster Properties and Pfam Annotations

Number of structural domains191
Mean domain length (aa)212 ± 33 aa
Standard deviation of domain lengths33.24
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score84.86
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)24.92
Pfam Score68.35
Assigned Pfam label(s) PF04998- PF04992- PF04983- PF00623- PF05000

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A835VFK8 2-227 DYLLFFLRDYNVFAAASCMNRLAKLSARWIGNHGFSIGIDDVQPGERLNQQKKRTIDDGNRECREFITKYNKAELTLQTGCDAAQTL…
A0A833E2T6 2-154 VLSAARKKVEDIVVNYLDPFNNVFIMARTGARGNELNITQMAALLGQQSVRGERIYRGYRDRYLPHFRSGDLGAAARGFVYSSFYEG…
A0A843E157 280-526 None
F3KFL6 5-216 None
A0A835R4S9 608-824 None
A0A6A4GUT0 43-281 None
T1GNZ5 299-511 None
T1H0L1 3-163 None
A0A662MCS6 877-1119 None
A0A2H2IYM4 386-641 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.