DPCstruct | MC13540

Metacluster Properties and Pfam Annotations

Number of structural domains191
Mean domain length (aa)212 ± 33 aa
Standard deviation of domain lengths33.24
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score84.86
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)24.92
Pfam Score68.35
Assigned Pfam label(s) PF04998- PF04992- PF04983- PF00623- PF05000

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A821S139 184-428 None
A0A6L2NQ34 240-475 None
A0A0E0JVN1 293-514 None
A0A835IIY4 90-322 None
A0A2K1IWL6 144-396 None
A0A7V4MZ36 226-456 None
A0A3M0LFQ1 181-386 None
A0A4V1SY40 5-129 None
A0A1V3WKY8 103-315 None
A0A4Y9XXH3 321-520 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.