DPCstruct | MC13453

Metacluster Properties and Pfam Annotations

Number of structural domains233
Mean domain length (aa)134 ± 23 aa
Standard deviation of domain lengths22.79
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score77.46
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)35.64
Pfam Score91.41
Assigned Pfam label(s) CL0264- PF14416- CL0016- CL0650- CL0133

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3Q7IBW4 753-885 None
A0A834HCI6 11-154 None
A0A5P1E5F4 470-605 None
A0A2G9I7Z4 50-179 None
A0A498HFY7 22-155 None
A0A498HSU9 3-93 None
R1G1U3 18-169 None
A0A2I4HSG1 118-281 None
A0A1D6L7M5 24-114 None
A0A4D9C7B5 108-269 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.