DPCstruct | MC9912

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)177 ± 23 aa
Standard deviation of domain lengths23.17
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score83.74
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)25.14
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5R9DHM8 24-198 EQVYSEFDDEMKTLQEQIDSLTQENEALRAENAGLHSKFGEMDKRPALVMGDEEDLYPGEIKELVLSVLADKLERRVAKRSRRSEVF…
A0A1H6HQ27 18-186 DNTIDMLNIDIEVLKEENERLQKIIDERARGQTVSLNDGLISRGQEADLYPNEVREILMDVLKAARANIVKDGTRRADVVDDILKAN…
A0A3D1UPY6 1-128 None
R5ECV1 20-155 None
A0A3C0TZR3 68-253 None
A0A286E496 127-335 None
A0A1C6J9U0 236-421 None
A0A350IYL4 462-634 None
A0A6N3UVL0 308-479 None
A0A1U7J586 228-419 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.