DPCstruct | MC9774

Metacluster Properties and Pfam Annotations

Number of structural domains52
Mean domain length (aa)227 ± 36 aa
Standard deviation of domain lengths36.02
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score73.07
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)27.56
Pfam Score97.56
Assigned Pfam label(s) PF05454- PF15445- CL0656

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W4J7I5 2-170 WKTTEIAAAMELAKQAGAAKGAAAGLKAGVDAVITGLKELGVKDFCPDLLQSIGSKIHYTNAEQIANSILRKFNATCYLSNDITTDG…
A0A024WW07 234-461 DIHSDAIPTCICEKSMADKVEKGCLRCGSILGAAMPEVGSIGGGLLYALNAWKPAALLAATEYALAEGAAKGLAAGNVKGVEIVLLG…
A0A2P9A805 80-326 None
A0A024UY72 23-261 None
A0A0L1I650 66-335 None
A0A0L1I5Q9 51-288 None
W7F8B6 1-227 None
W7FQN3 1-190 None
A0A024VW66 2-166 None
A0A024VK06 51-304 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.