DPCstruct | MC974

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)119 ± 14 aa
Standard deviation of domain lengths13.89
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score86.63
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)35.03
Pfam Score97.73
Assigned Pfam label(s) PF07286- CL0158

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S8SY05 6-99 MEPKEVRRLIREGKITKTTSGMCAGYAQADLVILPKDFAYDFLLFTQRNPKSCPILEVSDVGSRSLNYIAEETDIAKDIPKHRVYKD…
H1SC78 9-121 LMPFDFRQAVRSGQFRGPTAGYCGDHAQANLAILPSAHASDFLRFCQANPKPCPLLGVGEPGQWHVPVLGREVDIRNDVPAYNIYRD…
E4XTM2 90-215 None
A0A2B7X838 6-116 None
N4VMA5 5-138 None
A0A7J6UMR5 49-186 None
A0A6N9Y7W8 1-86 None
A0A225B8V9 14-146 None
A0A2K5UV09 305-425 None
A0A672SF83 3-101 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.