DPCstruct | MC973

Metacluster Properties and Pfam Annotations

Number of structural domains91
Mean domain length (aa)354 ± 69 aa
Standard deviation of domain lengths69.46
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score85.88
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)24.20
Pfam Score97.78
Assigned Pfam label(s) CL0062- PF19278- PF06032- CL0108

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2X5DC53 2-290 LNRVVQRRGMEVGLICNKGFEQMHSMGRALQSYLGYALEERLHINTHKYDDPLIPLKRIRGVTERTDVKGQVVIPVRQEEVKVAVKE…
H1SB19 17-386 RWQFWIDRGGTFTDVVGFQPDGTIVTHKLLSENPEQYNDAAVAGIRHLLGLAPGEPVTPAQVEVVKMGTTVATNALLERKGEPVALF…
H0EM88 2-438 None
F3NJY9 5-287 None
A0A1I5VRE7 2-276 None
A1ZD09 71-406 None
A0A6A6Z204 38-291 None
A0A6J7HYF7 1-231 None
A0A6M0F5R8 9-265 None
A0A5C4M151 2-307 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.