DPCstruct | MC9528

Metacluster Properties and Pfam Annotations

Number of structural domains645
Mean domain length (aa)195 ± 38 aa
Standard deviation of domain lengths38.09
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score83.28
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)13.47
Pfam Score91.13
Assigned Pfam label(s) CL0214- CL0028- PF06074- CL0247- CL0007

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S3ERK2 841-1040 None
A0A0D2WNZ3 161-346 None
A0A7Y1V067 6-248 None
A0A7W7BWY5 28-222 None
A0A2P6R7A5 2-148 None
A0A535MUM4 287-487 None
A0A433P5Z5 36-281 None
A0A5J4Y510 28-182 None
A0A814ZVW5 23-254 None
A0A6A5HPZ0 172-384 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.