DPCstruct | MC95

Metacluster Properties and Pfam Annotations

Number of structural domains71
Mean domain length (aa)603 ± 91 aa
Standard deviation of domain lengths90.95
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score78.10
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)13.83
Pfam Score73.39
Assigned Pfam label(s) PF21013- CL0020- PF09172- PF06448- PF19444

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A662YWV2 28-582 LGKGNLAALEKPLILHLNFGKVKSLYSYRKEHAVFKNIKRGLVSLFQLQLSSGRGEEMDVSGKCKVNYQARQNQVTRIKELDSCKTA…
A0A6H5ITV8 267-1011 VDRRREELDVHGVCETTYRLHEARRTSLVLRKSKSLATCRQAGKHLSLVQSHAYRSPLARVHALRQPLVASSSECDITIDHNVYERV…
K1PY02 144-810 None
A0A066S0N5 45-651 None
A0A4Y2LD08 15-616 None
A0A2H2IZF9 2-485 None
A0A7R9B8J5 20-593 None
A0A498NTS6 130-791 None
A0A5B7CUZ6 3-633 None
A0A5K4FCN8 95-648 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.