DPCstruct | MC9495

Metacluster Properties and Pfam Annotations

Number of structural domains37
Mean domain length (aa)106 ± 20 aa
Standard deviation of domain lengths19.85
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score83.95
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)23.16
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S2DLE5 1-67 MEKQEFQVGDMIYCIDEDYREFEDIVVSVELERDGTICYTGDNGWDFFKEDIGKEIFRTREERSKFL
A0A174XHX1 37-135 KEYEDVGLEPDEIRKLAEYRRLEDQKQLVKLPCKVGDIVYGTFAGRVSECFCIGWKYTGGGLYMICMDRENHQNYSFFDFLFGEKWF…
A0A3E4YLX9 30-139 None
A0A1Y4MII2 47-145 None
A0A4R2K833 23-116 None
A0A355TLN7 87-199 None
A0A3R6TGZ9 24-143 None
F0SXF1 38-145 None
A0A858MXP3 24-135 None
A0A3R6P183 5-95 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.