DPCstruct | MC945

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)122 ± 10 aa
Standard deviation of domain lengths10.11
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score86.86
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.89
Mean intra-cluster local Distance Difference Test score0.92
Mean intra-cluster sequence similarity (%)58.29
Pfam Score100.00
Assigned Pfam label(s) CL0115

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5A7PK53 81-193 GEDSAQFVLSQQKISSWVYFSVILGVVLYVLDVAWIDNSTGFGKVFIDALSAFSGSPEVVMLLLTLIFAVVHSGLASLRDTGEKVIG…
A0A699Y8H9 1-126 MKGEDAAQFDIQQQSAQSWTIFFGLLTGVLGLLYLVWIQPGVGLADDYVATIQAATDSNPEATIIAILAVFALFHSGLAALRPAGEK…
A0A498JZQ7 542-656 None
A0A2U1LRK7 219-345 None
I3S2G3 68-180 None
A0A150G3T2 938-1050 None
A0A7S2UFW7 91-233 None
A0A453JLE7 1-122 None
A0A6L2MLU7 29-141 None
A0A2P6TGT3 220-354 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.