DPCstruct | MC9243

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)132 ± 30 aa
Standard deviation of domain lengths30.09
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score91.26
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)50.12
Pfam Score100.00
Assigned Pfam label(s) CL0004

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4R8H195 1-111 MRHLRRGGTPCVAAHSTTRALYAAYDGPLYQVRRASDNTVKDIGVLSTGGYANAAAQDSFCAGTSCVITVIYDESGKGNHLAQAPRG…
A0A4V2AJF4 307-409 YGAANNTCVAAHSTTRALLSAYSGALYQVKRADGMTKDIPVKSPGGYADSAQQDTFCAGTTCTIWRIYDQSGHGNFLEAETPESTVK…
A0A0A3XKD5 401-509 None
A0A495TNN0 30-188 None
A0A7S4R4P7 123-230 None
W7TC56 1-190 None
A0A2I0RY56 1-163 None
A0A553HUS4 1-162 None
A0A1C4RUF8 30-169 None
A0A067SK68 63-160 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.