DPCstruct | MC9075

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)188 ± 32 aa
Standard deviation of domain lengths31.76
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score84.68
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.88
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)52.28
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D0N616 3-189 LVWWLFMGVFPLALQMRSYTQFVRPTRMSEILVVPQAQQVETANLTDFCPVEAFVLAGVWWNFEPTHYYTTDNGTVCHAVIPQYNTH…
A0A6A4FD69 33-208 LFLMWMSIGVAPLLLQARSYVRYVTPHKISKSLLPLEADVHETADLLDNCPVEGLFVAGIWWNVTPLYYFQAQDGKLCHFVVPQYNI…
W2GFP0 17-212 None
W2YU19 519-729 None
W2ZJC9 432-635 None
D0N4Z7 1-178 None
D0N2X7 2-179 None
W2LFM1 35-241 None
W2IJB1 222-487 None
A0A662XNE3 21-217 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.