DPCstruct | MC8949

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)207 ± 24 aa
Standard deviation of domain lengths23.63
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score87.06
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)28.67
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6I9NID3 28-215 CGTGDPTVTVPRGLRCSNPERRKKLVLHVDLNNTILVSDSVIAQGTVAALEHFLSTVTWGRMSKGKWEWLSGSPSLHPPCDGAVSYH…
A0A2P4T887 9-193 RLVLHVDLNNTVVAADAVSGLGPREALNIFLSTATWGREGADGEWQWMSDRPSLRAPCPGAVSYYCRYGRAQDFTESGPGQRFSSLH…
A0A1Q9D1W4 360-535 None
A0A812IZU0 28-301 None
B7G4B5 10-230 None
S9TR77 12-201 None
A0A0M0K9A9 166-355 None
A0A812SQY4 125-341 None
A0A1I8GXU9 40-243 None
A0A024GJX9 4-218 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.