DPCstruct | MC8929

Metacluster Properties and Pfam Annotations

Number of structural domains727
Mean domain length (aa)274 ± 72 aa
Standard deviation of domain lengths71.56
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score84.44
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)11.56
Pfam Score93.45
Assigned Pfam label(s) PF16466- PF20954- PF20953- PF05105- CL0021

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A105TQQ4 9-252 NAITKTTNFAIIDYLIDPRKNNLMSYGYFFNSSIFAGKATINRKAETSSAHDVAKRIFSKVQFQPTTTIQHASSETDPRNLLFINFA…
A0A2S6NI59 52-300 ASVEGRDLSASLVDSYRQLDFVNQTASQVVATIANWHSLEAIVTPTSGNTGRYFGEGYTRLSTGLYSRLCSDWDLVVQLARESNFDA…
A0A843PDU2 25-278 None
A0A250FYV6 53-358 None
A0A843GBX2 88-415 None
A0A3S0YGL1 3-175 None
A0A842MQ94 441-787 None
A0A4V1QX63 9-493 None
A0A376F976 7-217 None
A0A7V9V7F8 11-196 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.