DPCstruct | MC892

Metacluster Properties and Pfam Annotations

Number of structural domains36
Mean domain length (aa)212 ± 29 aa
Standard deviation of domain lengths28.66
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score79.44
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)38.13
Pfam Score98.15
Assigned Pfam label(s) PF15024- PF15027

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4W4HB08 148-361 ASKVDWMRARWTSDPCYAFYGVDGSDCSFLIYLSEVEWFCPPLPWRNHSSQSTVSSAPERQAMVRSDLGPLLEQLGSGKESLSFMRR…
A0A060W2I2 19-237 ISFFSNTNTLALHSQFLQARWDSDLCYAFYGVDGTTCSILTYLSEREDFCPPHPGRNHSAPPWHQQPHTHKEKAEVRTTLRPLYEVF…
A0A2R5FZV0 65-353 None
A0A315VFB5 591-800 None
A0A1S3R9K7 22-198 None
A0A7D9DQN7 58-309 None
A0A401S6K6 59-264 None
R7T9E6 146-386 None
S4RE96 5-169 None
A0A3P6QVN6 674-894 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.