DPCstruct | MC8887

Metacluster Properties and Pfam Annotations

Number of structural domains45
Mean domain length (aa)275 ± 34 aa
Standard deviation of domain lengths33.73
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score82.81
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)13.93
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A374DIG1 97-387 IEKAISFEKKSLQDFEEVIRQNPKIPDKFKPLMEEYCKCVFEKYPDVELRPFYQNLQSLEVVECTEDELLKVSWDVYSCGCYVKSEN…
R5JB94 36-306 LNKQKHSDVYKIIDDFSATNIPLDTNLDNIEQILQNLSYPDELKEIIRTFKNYIEPVNFETCINRLGSLKINYVSLLHDIKKYSQNF…
A0A831ZYX7 9-263 None
A0A353SZQ8 174-499 None
A0A3D0XYB6 1-322 None
R5VGB0 91-341 None
R5VPT6 15-250 None
A0A2M7V8E9 153-436 None
R6YL17 5-238 None
A0A0G1LH53 1-367 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.