DPCstruct | MC8883

Metacluster Properties and Pfam Annotations

Number of structural domains722
Mean domain length (aa)236 ± 57 aa
Standard deviation of domain lengths57.01
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score74.22
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.41
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)16.69
Pfam Score98.59
Assigned Pfam label(s) CL0020- CL0105- PF03004- CL0036- PF13960

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0J8B4A9 5-149 IQPIDVWHSRGVRYHVQFNEFNQPIRKGGHILVRFLGSVAKDGTYCPIGEKNWHHVDAKLKTKIVMKMREHFVILEDEVYNTLALQR…
A0A1S4DGU4 11-250 NKSKKGRGKYKSLQVDMKTKHGSKIPIVIPDDIMRAVGPGSRDIVNYCGLIMRSTISFRDGNWQAIIAKHGEAMWLKVKDKFEASGM…
A0A1R3KP73 403-728 None
A0A1R3KPL4 15-304 None
A0A1R3KPT5 847-1145 None
A0A803Q2I8 8-233 None
A0A5E4F371 2-227 None
A0A6V7PEQ9 1-235 None
A0A445CTZ0 63-359 None
A0A445DGR6 1-213 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.