DPCstruct | MC8818

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)350 ± 50 aa
Standard deviation of domain lengths50.31
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score76.05
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)34.97
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6J8BL20 33-383 LKCEIEVYQKRLDAKYKAIAILREQSKKLQDFREVQKKKSYIYNHSLEQEVNKLHFELDQKEVSLENSQAIWAERFDNVCRENSSLT…
A0A224Y861 47-316 DEVSSLQSELDICRRLLNAKYLAAHILLKQLVRVSEEKEEGTRQSHRQCAQLLKELNGLQYELQCMEEHLRRSQQAWLDRLNSLVQE…
A0A7I8VTP8 109-419 None
H3C647 2-299 None
A0A6P8SVZ1 1-440 None
A0A553NKG4 69-409 None
R7ULK9 181-567 None
B2RYD1 2-292 None
H2RXI5 1-456 None
A0A812APQ6 159-514 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.