DPCstruct | MC88

Metacluster Properties and Pfam Annotations

Number of structural domains39
Mean domain length (aa)78 ± 12 aa
Standard deviation of domain lengths11.61
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score91.53
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)32.05
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2G4J4E3 199-284 SLIARHLEAHGIPTVLMGCAKDIVEHCGVPRFMFSDFPLGNSAGKPHDLASQRQTLVLAFKVLETAVVARTTVQSPQRWGQSHEWK
A0A0S8KNU1 1-82 MSTVLVTNMPFWAERAGAPRTLAVEFPLGQPRNAAQQMRVIRQALEVLETADTPGTIVHSEEAWPLPPEQALEEWQPAVPSP
A0A2E4HIL7 7-101 None
A0A4R2JAT4 587-671 None
A0A7C1NC54 2-72 None
A0A3C1G6H2 2-54 None
A0A2E7Z288 6-68 None
A0A6L8E3C1 8-87 None
A0A6N7Y2P7 6-78 None
A0A523DBE1 213-293 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.