DPCstruct | MC8746

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)137 ± 14 aa
Standard deviation of domain lengths13.78
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score86.99
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)22.62
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2L1KG79 5-124 EALTALYNELDRVGVGLILKHWSGNQWALVLPDASEPGKFRYQAFGLHGWITHHTCTTLDEVVSDAFCAGFRMVASPDTLDRVASTV…
A0A6I1NQ26 7-162 RCDFAVRAANLRVSFTDTGKDDASLNVWVEQAAKELEEKQVVLDAMLKLYDEQGIGSIYKDKHGRYGFVLADASEEGAFRYQLFDAN…
A0A5B0SVP7 10-130 None
A0A7X4XER3 39-204 None
A0A192A898 18-153 None
A0A1Z3ML06 15-136 None
A0A2N4UQ08 23-178 None
A0A7Y8GX49 8-137 None
A0A2N2AMG5 271-389 None
A0A2E6Z818 54-208 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.