DPCstruct | MC8736

Metacluster Properties and Pfam Annotations

Number of structural domains125
Mean domain length (aa)287 ± 74 aa
Standard deviation of domain lengths73.90
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score79.94
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)27.24
Pfam Score99.12
Assigned Pfam label(s) PF00375- CL0227

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A645I6F2 2-175 TVIYYFGFFTLYAYIAAGKKGISAFWRNALAPSVTAIATCSSAASIPINLVATKAIGVPKDTAETVIPLGANIHKDGSVFGGVLKVV…
A0A0C2QM49 20-324 DGLGKEKQSTLGKLLVETEKRSDRTAEADGFNMKSFVSMLIPTNIFDALYHEKNLQVLFFSVVFGIGVGLIRSPASGHILAAGETIF…
A0A835NNJ4 207-520 None
A0A347WI18 2-205 None
A0A522CMV1 252-661 None
A0A5J5CR95 36-439 None
G1T525 53-354 None
A0A158QUW3 572-943 None
A0A7C1PWK5 74-413 None
A0A3B4UV74 50-320 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.