DPCstruct | MC8686

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)75 ± 12 aa
Standard deviation of domain lengths12.17
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score66.23
Mean fraction of residues predicted as intrinsically disordered0.45
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)35.63
Pfam Score88.89
Assigned Pfam label(s) PF06817- CL0010- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q2HHY7 263-328 LPLQSRVRVWREKSRRWEGPFTLIGVHDEDCIVETSRGAQKFRSTVVKPYYEDPAQQDDPANQKDT
G3GXW0 1-91 MSNLLQIDSGIQATFAQVKWKDHCTGLQKGPDPVLIWGRGHVCLFFSQEENEVQWLPECLVRCVEQSKANPDGAVTAGPPPEELEQD…
A0A6P9D050 1-100 None
A0A3M0IT78 111-195 None
A0A3M0IRU0 911-975 None
A0A3M0IR00 35-107 None
A0A3M0L9B8 325-394 None
A0A3M0L1Q8 383-450 None
A0A3M0KJP4 188-258 None
A0A3M0L9E6 267-326 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.