DPCstruct | MC8676

Metacluster Properties and Pfam Annotations

Number of structural domains169
Mean domain length (aa)246 ± 51 aa
Standard deviation of domain lengths51.01
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score81.65
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)33.16
Pfam Score96.45
Assigned Pfam label(s) CL0031- CL0229- CL0266- PF12578

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A670ZXH0 306-460 SRWLSNVESTHWLEYIRMLLAGAVRIADKIESGKTSVVVHCSDGWDRTTQLTSLAMLMLDSYYRTIKGFEVLLEKEWMSFGHRFAMR…
A0A833ZED3 19-259 SHWLSSLESTHWLEHIKLVLTGAIQVADKVSSGKSSVLVHCSDGWDRTAQLTSLAMLMLDSFYRSIEGFEILVQKEWISFGHKFASR…
A0A6P8IBS5 460-726 None
M2RDT6 694-912 None
A0A3Q0IYJ0 81-251 None
A0A7R9KGB5 342-561 None
A0A6I8PLV7 269-513 None
A0A0M8MY17 768-1199 None
A0A6P4EEV9 412-704 None
A0A4W4DXH8 267-527 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.