DPCstruct | MC863

Metacluster Properties and Pfam Annotations

Number of structural domains472
Mean domain length (aa)173 ± 38 aa
Standard deviation of domain lengths37.56
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score76.38
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)23.88
Pfam Score84.71
Assigned Pfam label(s) CL0023- CL0028- PF14214

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6P5NIL0 7-176 KESNLQSVEIVDEFICVELPNPLKFPALYNVVTKYMIHGPCGQLRPSSPYMKDGKCSKFYPKRFVDQTRFDEDGYPIYRRRNMGVTV…
A0A2S2R808 2-97 IDKFVCAEIPNPDVDPLLYEIVKANMIHGQCGLLNKNSPCMKGGVCSKRYPVTLIQETQRGEDGYPKYRRRSTNDGGFKVSIESIDL…
A0A5C2SKM6 41-185 None
A0A284RAN5 818-1027 None
A0A146H3V4 714-912 None
A0A4Y2CYN3 2-160 None
A0A1U7Y1G0 354-468 None
A0A4Y2CC74 44-185 None
A0A4Y2CC33 3-154 None
A0A6V7PWG3 27-171 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.